Concerta vs. Ritalin: An ADHD Medication Comparison
Concerta and Ritalin are both stimulant medication formulations containing methylphenidate hydrochloride, a chemical compound that produces stimulation by increasing dopamine and norepinephrine levels in ADHD brains. The end result for many: improved focus, reduced impulsiveness, and dampened hyperactivity. Compare and contrast these popular ADHD medications here.
Concerta vs. Ritalin
Concerta and Ritalin are stimulant medications used to reduce symptoms of ADHD. These medications are different brand-names for the same drug, called methylphenidate hydrochloride (MPH), which a new meta-analysis identified as the most effective first-line treatment for children with ADHD.1
Since these popular medications are made from the same chemical compound, they both act similarly — they do not cure ADHD, but they can increase focus and reduce impulsiveness and hyperactivity. The main differences are in the length of effectiveness, the strength, and the dosage.
ADHD Medication Summary
Concerta and Ritalin share the same active ingredient. However, Ritalin is a short-acting stimulant that boosts focus and attention quickly. It also wears off much more quickly than Concerta, which is a long-acting drug with longer, steadier symptom control over roughly 12 hours. Some patients report a more abrupt onset and offset with Ritalin, but other side effects — namely, appetite and sleep trouble — are very similar.
According to a 2017 survey of ADDitude readers, 42.28% of children with ADHD have used Concerta at some point and 32.37% have used Ritalin at some point. That makes these medications among the most popular among children. Among adults with ADHD, 27.68% have used Concerta and 33.27% have use Ritalin, the most commonly used after Adderall.
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Among those who have used Ritalin and Concerta, the medications’ efficacy is rated in the chart below, which also tracks the percentage of patients who experienced three common side effects.
Pediatric Patients: Concerta vs. Ritalin
Medication | Extremely or Very Effective | Not Very or Not at All Effective | Irritability or Moodiness | Sleep Problems | Dampened Personality |
Concerta | 44.65% | 22.52% | 34.10% | 32.69% | 22.48% |
Ritalin | 38.87% | 21.77% | 36.18% | 28.31% | 23.79% |
Adult Patients: Concerta vs. Ritalin
Medication | Extremely or Very Effective | Not Very or Not at All Effective | Irritability or Moodiness | Sleep Problems | Dampened Personality |
Concerta | 36.00% | 29.06% | 23.91% | 26.09% | 13.59% |
Ritalin | 40.77% | 21.62% | 23.57% | 20.14% | 16.7% |
ADHD Medication Comparison
Concerta | Ritalin | |
Manufacturer | Janssen | Novartis |
Compound | Methylphenidate tablet with osmotic pump technology; biphasic release with initial peak at 1 hour (22% of dose) and 78% gradual release over 9 hours | Methylphenidate HCI |
Approved Ages | Over the age of 6 | Over the age of 6; Sometimes used for children younger than 6 |
Formulations | Extended-release tablet | Short-acting, immediate-release tablet Ritalin LA (Long acting) extended-release capsule |
Considerations | Potentially dangerous when used by people with heart problems Must be swallowed whole Not-absorbable shell may be passed in stool |
Potentially dangerous when used by people with heart problems Abrupt onset and offset increase the number and severity of side effects |
Window of Effectiveness | 8-12 hours | 3 to 4 hours for short-acting 8 to 10 hours for extended release |
Side Effects | Headache Stomach ache Trouble sleeping Nausea Decreased appetite Nervousness |
Headache Stomach ache Trouble sleeping Nausea Decreased appetite Nervousness |
Generic available | Yes | Yes |
ADHD Symptom Control
Despite chemical similarities between Concerta and Ritalin, different patients will react differently to these medications. For example, when discussing Concerta, one respondent to ADDitude’s 2017 ADHD treatment survey said, “It has always been extremely helpful for me to get stuff done,” while another said, “It didn’t help at all; discontinued after two months.”
The same goes for Ritalin. One person felt it provided “help with focus and initiation of work and task completion,” while another said, “It left me feeling dull and moody.”
While it’s true that individuals react to the same medication in very different ways, it is also true that roughly 30% of all ADHD patients do not get a benefit from or cannot tolerate taking any MPH.2 These people may report experiencing no benefits or feeling dull and moody. The logical next step for them is to try the other class of stimulant ADHD medication: amphetamine.
[Free Download: What You Need to Know About Methylphenidate Vs. Amphetamine]
The experiences and feedback of other patients are interesting, but not necessarily helpful as you weigh your own or your child’s medication options. Each individual processes, metabolizes, and reacts to medication differently, and there is currently no reliable way to predict how any given medication will impact one individual.
Medication Dosage
Ritalin is available in short-acting and extended-release formulations, each with its own dosage options.
Ritalin and Concerta dosages are based on how an individual metabolizes medication — not on height, weight, and/or age. Your doctor may start with the lowest dose and slowly increase it depending on your response. When starting the medication, it is helpful if you keep track of the dosage, how it affected your ADHD symptoms, and how long it lasted. This information will help you and your doctor determine your ideal dosage.
For further details on Concerta and Ritalin, including dosages, precautions, and interactions, visit the WebMD Drugs & Medication Database.
[Free Download: ADHD Medication Monitoring Sheet]
ADHD Medication Side Effects
Side effects from methylphenidate often disappear within a few weeks of starting the medication. However, for some people the side effects are severe enough to merit a cessation of the medication. The most common side effects with both Ritalin and Concerta include headache, stomach ache, loss of appetite, sleep issues, and nervousness. Less common side effects include dizziness, drowsiness, and anxiety. As with effectiveness, you should keep track of your side effects and discuss these with your doctor.
Anecdotally, adult patients who took the ADDitude treatment survey reported side effects including the following:
Ritalin
- “Makes me lethargic and lazy. Just like to watch TV on couch now. Just no ambition.”
- “Caused headaches and emotions like crying.”
- “My appetite eventually adjusted.”
- “Made my heart rate increase and blood pressure go up.”
Concerta
- “Jitteriness – felt like I was jumping out of my skin.”
- “Minor loss of appetite.”
- “Increased irritability and anger and dramatically changed my moods.”
- “Left me unable to sleep, headaches and constant stomach ache.”
Medication Warnings
Methylphenidate medication labels include warnings for potential serious cardiovascular events. Children and adults with pre-existing cardiac conditions or heart abnormalities should seriously discuss the use of these medications with their doctor and weigh their benefits and risks. If these medications are used, a patient must do so only under the close supervision of a doctor with consistent monitoring of the heart condition and blood pressure.
[ADHD Medication Side Effects That No One Should Tolerate]
View Article Sources
1Cortese S, Adamo N, Del Giovane C, et al. Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis. Lancet Psychiatry. 2018 Aug 7. doi: 10.1016/S2215-0366(18)30269-4
2Spencer T, Biederman J, Wilens T, Doyle R, Surman C, Prince J, Mick E, Aleardi M, Herzig K, Faraone S. A large, double-blind, randomized clinical trial of methylphenidate in the treatment of adults with attention-deficit/hyperactivity disorder. Biol Psychiatry. 2005 Mar 1;57(5):456-63. doi: 10.1016/j.biopsych.2004.11.043. PMID: 15737659. DOI: 10.1016/j.biopsych.2004.11.043